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Medical Practice Startup Consultant: Start or Open a Practice in Florida

If you are weighing a medical practice startup consultant, start with timing: the 13 filings below wait on one another, and Medicare's effective date is the later of the day you file and the day you first see patients at the location (42 CFR 424.520(d)). We handle initial enrollment and credentialing with Medicare, Medicaid and commercial plans, and coordinate with your attorney on the legal questions.

The short answer

What does a medical practice startup consultant do?

Helps you sequence the 13 filings a new Florida practice makes, which wait on one another, starting with the entity on Sunbiz, and time credentialing: Medicare's effective date is the later of the day you file and the day you first see patients at the location. The Advixor Group handles initial enrollment and credentialing with Medicare, Medicaid and commercial plans, and coordinates with your attorney on the legal questions.

Sources42 CFR 424, subpart P

Every Filing

Start a medical practice in Florida: the filings, in order

Filing Agency Government fee ($) Needs first
Professional entity (PA or PLLC) Division of Corporations (Sunbiz) LLC 125, corporation 70; fictitious name 50 —
EIN IRS 0 Entity
Practitioner licenses DOH boards MD: 350 + 355 —
Clinic license or exemption AHCA 2,000 + 300 per 2 years, or 100 for a certificate Entity, director, Level 2 screening, location
Certificate of use (City of Miami) City zoning, DERM, Fire, Code Enforcement 50, plus inspections Lease
City business tax receipt City of Miami Invoiced Certificate of use, state licenses
County business tax receipt Miami-Dade Tax Collector By classification State licenses, city receipt
NPI Type 2, plus a Type 1 per clinician CMS (NPPES) 0 Entity, EIN
CLIA certificate, for any in-office test CMS, through AHCA Waiver 248, PPM 297 per 2 years Location
DEA registration (Form 224), per prescriber, state and dispensing site DEA 888 per 3 years Florida license
Medicare, group and each clinician First Coast 0 NPIs, location
Florida Medicaid AHCA 0 for physicians, NPPs and Medicare-enrolled providers Fully operational office
Commercial plans Each plan None published Licenses, NPIs, malpractice coverage

Sources Sunbiz; Board of Medicine; AHCA Form 3110-0013; City of Miami; Miami-Dade Tax Collector; IRS; CMS; 21 CFR 1301.13; 42 CFR 424.514, 455.460; Cigna; Evernorth; read Oct 17, 2026.

Your Entity

Starting a new business in Florida: entity, names and tax numbers

  • Entity: a PA or PLLC may issue shares or admit members only to licensees (or professional corporations and PLLCs) authorized for “the same specific professional services” (s. 621.09), and its name must carry “chartered,” “professional association” or “P.A.”, or for a PLLC formed since 2014, “PLLC” or its long form (s. 621.12(2)).
  • Names: you may not trade under a fictitious name until it is registered, and the registration runs to Dec 31 of the fifth year; AHCA and Miami-Dade both ask for it (s. 865.09).
  • Annual reports: due May 1: $138.75 for an LLC, $150 for a corporation; $538.75 and $550 after.
  • EIN: issued immediately online, one per responsible party per day, in a session that expires after 15 minutes of inactivity; you need that person’s SSN or ITIN.

Licenses

Medical practice startup licenses: DOH, AHCA, CLIA and DEA

The Department of Health works to the general licensing clock.

An MD license adds a NICA fee of $0, $250 or $5,000 by designation, and proof of financial responsibility, such as malpractice coverage of $100,000 per claim and $300,000 a year (s. 458.320).

  • AHCA: a clinic that needs a license files Form 3110-0013 with proof of financial ability (Form 3100-0009) and the director’s attestation (Form 3110-1028).
  • CLIA: Form CMS-116 goes to AHCA; CMS emails a fee notice with your CLIA number, you pay on pay.gov, and testing starts only once the certificate arrives. A waived lab’s director needs no federal qualifications.
  • DEA: registering to prescribe Schedule II–V drugs requires one-time training of at least 8 hours on substance use disorders, unless, as a physician, you hold an addiction board certification, or you graduated in the last 5 years from a program that included 8 hours on it (21 U.S.C. 823(m)).

“An application for a license must be approved or denied within 90 days after receipt of a completed application unless a shorter period of time for agency action is provided by law.”

s. 120.60(1), Florida Statutes (2026)

Local Steps

Local steps to start a business in Florida: Miami-Dade and the City of Miami

  1. City of Miami certificate of use: the City replies within 5 business days, and the DERM, Fire and Code Enforcement inspections must finish within 90 working days of starting, or you start over and pay the non-refundable $50 again. It expires every Sept 30.
  2. City receipt: it also asks for the EIN and each professional’s SSN and photo ID, and an interim receipt comes by email. Other cities set their own rules.
  3. County receipt: every applicant signs a declaration under s. 205.0532 on whether it does business with Cuba in violation of federal law (a knowingly false one is a third-degree felony). Printing takes up to 3 business days after that; operating without a required receipt adds a 25% penalty (s. 205.053(2)). Offices in unincorporated Miami-Dade also need a Certificate of Use and Occupancy.

Credentialing

Opening a new medical practice: credentialing before day one

Florida Medicaid gives you 21 days to fix a deficiency before it denies the application; Cigna adds about 10 business days to load an approval.

How long a new practice’s applications take, in days: published figures and legal deadlines
DOH initial review, MD (Oct 17, 2026)14 days
DOH initial review, APRN (Oct 17, 2026)25 days
Medicare, every clean online file50 days
AHCA clinic license, once complete60 days
Florida Medicaid, AHCA’s estimate60 days
Cigna, before loading60 days
Medicare, with a site visit or fingerprints85 days
Evernorth behavioral health90 days

Sources DOH dashboard; s. 408.806(3), F.S.; First Coast; AHCA Medicaid readiness tool; Cigna; Evernorth; read Oct 17, 2026.

Employer Filings

Setting up a medical practice: employer filings and permits

  • Workers’ compensation: required at 4 or more employees outside construction, counting corporate officers and LLC members (s. 440.02).
  • New hires: reported within 20 days of each hire (s. 409.2576); with 25 or more employees, E-Verify too (s. 448.095).
  • Biomedical waste: a DOH generator permit before opening unless the office makes under 25 pounds in 30 days ($85 by Oct 1, $105 after, yearly) (s. 381.0098).
  • X-ray: apply to register each machine with DOH (DH Form 1107) within 30 days of acquisition and before use (Rule 64E-5.511(2)).
  • Prescription drugs: an entity that buys them needs a DBPR Health Care Clinic Establishment permit ($255 every 2 years) and a designated practitioner.
  • Pain management: DOH registration or a certificate of exemption if you advertise it or, in any month, most patients get opioids, benzodiazepines, barbiturates or carisoprodol for chronic nonmalignant pain (s. 458.3265).
A woman in a dark suit holds a clipboard inside an unfinished office space

Consultant or Attorney

What a medical practice startup consultant handles, and what stays with your attorney

Our medical practice startup consulting covers the payer, NPI, policy and hiring work in the cards further down, plus market research, a feasibility assessment and coordinated HIPAA, OSHA and fraud, waste and abuse training.

We prepare and submit the AHCA, CLIA, DEA and local filings.

The entity choice, operating agreement, lease and any purchase contract go to your attorney.

Quick answers

Questions for a medical practice startup consultant: NP and RN owners, buying, cost

Whether a nurse practitioner or a registered nurse can own the practice, buying one instead, what the government fees add up to and what to file first. For your own plan, ask us in a consultation.

Two professionals plan a new space together, one pointing at a printed floor plan
Starting a nurse practitioner practice: can an NP open one in Florida?
Para. (g) of s. 400.9905(4) exempts practices wholly owned by the licensees it lists, including APRNs (s. 464.012), if an owner who is a licensed practitioner supervises the business and is legally responsible for compliance. The sentence closing s. 400.9905(4) requires a clinic license to bill PIP unless s. 627.736(5)(h) lists the owner, and that list names no APRNs. Practicing without a supervising physician is a separate rule (s. 464.0123): see nurse practitioner credentialing. Whether your plan fits is a question for your attorney.
Can a registered nurse open a clinic?
Para. (g) names APRNs (s. 464.012), not registered nurses. A clinic that needs a license must appoint a medical director, or a clinic director if it offers no physician services (ss. 400.9905(5), 400.9935(1)). Whether your plan fits an exemption is a question for your attorney.
How do I buy a medical practice instead of starting one?
For a licensed clinic, the buyer's change-of-ownership application must reach AHCA at least 60 days before the sale, and the seller must notify AHCA by then (ss. 408.806(2)(b), 408.807(1)); a Certificate of Exemption does not transfer, so the buyer applies for a new one; and Medicare must hear of the ownership change within 30 days (42 CFR 424.516(d)). Due diligence and the purchase contract belong with your attorney.
How much does it cost to open a medical practice in Florida?
The government fees on this page come to $1,396 for a physician-owned, exempt office with an LLC, a waived lab, one DEA registration, a City of Miami certificate of use and a biomedical waste permit, not counting your own license (MD: $705 plus NICA) or the certificate-of-use inspection invoice; $3,696 if it needs an AHCA clinic license. Rent, equipment, insurance, payroll and local business taxes come on top.
What do I file first when starting a new medical practice?
The entity on Sunbiz: the EIN, the Type 2 NPI, the AHCA application and the tax receipts all ask for it.

Talk to an advisor

You care for patients. Who’s taking care of the business?

Tell us where your practice is today. We will tell you what we would do first.

Official sources